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KMID : 0861219990010020245
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Journal of the Korean Society Clinical Neurophysiology
1999 Volume.1 No. 2 p.245 ~ p.250
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Neurophysiology of Dystonia
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김재우/Jae Woo Kim
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Abstract
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-Abstract-
Dystonia is a movement disorder characterized by sustained, involuntary muscle
contractions leading to abnormal postures.
Using EMG recordings, three types of involuntary activity can be seen in dystonia.
There are abnormalities in many different types of reflexes in dystonia. In view of the
strong connection between the basal ganglia and motor areas of the cerebral cortex,
there have been several investigations suggesting defects in cortical function including
movement-related cortical potentials and contingent negative variation in patients with
dystonia. Although dystonia is considered as a movement disorder, there are several
phenomena relating to the sensory system that might suggest that dystonia could be
primarily a sensory disorder.
It is suggested that loss of inhibition from basal ganglia both at the cortical level and
brainstem and spinal cord leading to defective control of interneuronal excitability be an
important role for the pathogenesis of dystopia.
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